A Cross-sectional Study to Determine the Factors Affecting the Quality of Life in Patients with Grand Mal Epilepsy
Published: August 1, 2021 | DOI: https://doi.org/10.7860/JCDR/2021/49723.15219
Jagriti Yadav, Priti Singh, Surekha Dabla, Rajiv Gupta
1. Resident, Department of Psychiatry, Institute of Mental Health, Rohtak, Haryana, India.
2. Professor, Department of Psychiatry, Institute of Mental Health, Rohtak, Haryana, India.
3. Senior Professor, Medicine, Department of Neurology, Pt. B.D. Sharma University of Health Sciences, Rohtak, Haryana, India.
4. Senior Professor and Head, Department of Psychiatry, Institute of Mental Health, Pt. B.D. Sharma University of Health Sciences, Rohtak, Haryana, India.
Correspondence
Dr. Jagriti Yadav,
Pt. B.D. Sharma University of Health Sciences, Rohtak, Haryana, India.
E-mail: jagritipsyc07@gmail.com
Introduction: Epilepsy is a chronic neurological condition that affects various domains of life apart from causing physical dysfunction. It is associated with various cognitive and psycho-social complications that can adversely affect the Quality of Life (QoL).
Aim: To study the socio-demographic and clinical factors affecting QoL in Patients With Epilepsy (PWE).
Materials and Methods: This cross-sectional study was conducted at a tertiary care centre in northern India on patients with Grand Mal Epilepsy. Total 60 PWE were assessed for psychiatric co-morbidity using Mini International Neuropsychiatric Interview version 6.0 and were divided into two groups, Group I and Group II, based on absence and presence of psychiatric co-morbidity, respectively. Self-administered QoL in Epilepsy-31 Scale was then used in both the groups to assess QoL in the study subjects and statistical analysis was done. Normally, distributed quantitative data was analysed using independent t-test for two groups and Analysis of Variance (ANOVA) test for three or more groups.
Results: The mean age of the study population was 27.68±9.51 years. A 55% of the study population were males and 45% of total study population were females. The mean total duration of epilepsy was 7.42±6.98 years. There was significant main effect due to socio-economic status for domains of emotional well-being (F=7.513, p=0.010), energy/fatigue (F=5.625, p=0.021), cognitive functions (F=7.708, p=0.007) and overall score (F=6.876, p=0.011) on QOLIE-31 scale. There was a significant main effect due to total duration of seizure disorder for domains of energy/fatigue (F=2.724, p=0.03) and cognitive functions (F=2.852, p=0.03). The mean scores of PWE with psychiatric co-morbidity were lower than PWE without psychiatric co-morbidity in all the domains of QoL in epilepsy scale and the differences in two groups were statistically significant (p=0.01).
Conclusion: The present study showed that QoL in PWE is associated with various socio-demographic and clinical factors beyond seizure control.
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